Location : Oxford Road, Manchester
Closing Date : 18/03/2019
Salary : £32,236 – £35,211 per annum according to relevant experience.
Employment Type : Fixed Term
Faculty / Organisational Unit : Science & Engineering
Division : Chemistry
Hours Per week : Full time
Contract Duration : From as soon as possible for 12 months
This is a fantastic opportunity to take part in a new and innovative project to develop a novel biomedical imaging platform that could change the way we manage endometrial cancer, specifically by improving risk prediction for development of endometrial cancer.
Endometrial cancer (EC), of all cancers, has the strongest association with obesity, estimated to account for 60% of new cases, as a consequence of which the incidence of EC is rising sharply in post-menopausal women. Outcome is much improved with early detection, leading to high numbers of women with post-menopausal bleeding (PMB), the main symptom of EC, undergoing endometrial biopsy to determine if early cancer is present. However, negative biopsy does not preclude development of EC at a later date, leading to high degree of uncertainty for those with negative biopsies. Colleagues at St Mary’s Hospital Manchester have developed a prototype biomarker method for prediction of future risk of EC in women with negative biopsies, measuring the expression of 4 cell markers in endometrial biopsies. At present each of these markers is measured independently but it would be advantageous to measure them simultaneously. This requires a multiplex approach which this project seeks to develop and test. Read more